Meta: Moved my response to the appropriate thread.
You can definitely pull off a one-back offense in this game, but your playcalling has to be perfect.
I'm going back to a Harbaugh/Kiffin hybrid offense that combines a ton of one back and two back formations. Lots of West Coast passing concepts and zone runs. The scheme
can work in the game, but you have to center it around the passing game. If a user loads the box on you, you need to at least break even in the blocker:defender ratio. Often, you'll need a +1 advantage to account for the user defender running around like a dick.
If you're running the Erickson offense, you'll want to stretch the field more than he and Mazzone do. Yes, dink and dunk, but take deep shots. I noticed
@TXHusker05
mentioned you don't do that much. Against users, you HAVE to take deep shots early and often.
Go back and look at the film of National Championship this season. The Alabama offense struggled in the first half because they never took a deep shot. In the 2nd half, Saban told Kiffin to push the envelope, and the entire offense opened up because the defense was forced to respect the deep ball.
How you implement the deep ball into your gameplan is up to you. Personally, I use bootlegs and a few special plays to put a safety in conflict. If you're using the N-Zone as a base, Mazzone uses Y Cross and Four Verticals. Learn how to read those plays against various coverages and call them in the first drive of the game and as often as you can get away with it without getting a 3 & out. And yes, you will have a few 3 & outs using that strategy. These are high-risk, high-reward plays, but they're necessary to unload the box and run the ball.
At the end of the game, you want the stat line to be an even split between passing and rushing yardage (~150+ each). Early in the game, you're numbers will look skewed towards the pass (probably a 75%/25% split). That's what you want. Throw to score, run to win. Build a lead and then grind it out in the 2nd half. Once the D sells out to stop the run, go for another deep ball and make the killshot.